Back to search

Peptide record

TPDB06255

Antibacterial Anticancer Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB06255
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RCFRRRGKLTC
Physicochemical Analysis
C57H102N24O13S2
ANDEQHIMPSWYV
R
1395.71
11.95
5
0
2
+5
2.21
-1.036
35.45
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
125
8.96
3
Residue Composition
number
0
A
4
R
0
N
0
D
2
C
0
E
0
Q
1
G
0
H
0
I
1
L
1
K
0
M
1
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 1 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C57H102N24O13S2
1395.71
11.95
+5
2.21
-1.036
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

Escherichia coli ATCC 8739

Source & Reference

NA

Other

active against E. coli ATCC 8739 (MIC 4 ug/ml) and S. aureus (MIC 4 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

Staphylococcus aureus

Source & Reference

NA

Other

active against E. coli ATCC 8739 (MIC 4 ug/ml) and S. aureus (MIC 4 ug/ml).
Evidence 3 Activity

Activity

3.8% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
3.8% Hemolysis | 256 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Host-defense peptides AC12, DK16 and RC11 with immunomodulatory activity isolated from Hypsiboas raniceps skin secretion. | Peptides | 2019