Back to search

Peptide record

TPDB06247

Antibacterial Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB06247
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 11-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RWWRWWRRWWW
Physicochemical Analysis
C101H120N30O12
ANDCEQGHILKMFPSTYV
W
1946.26
12.88
4
0
7
+4
-9.71
-2.209
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
38500
1978.16
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
7
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 7 Y: 0 V: 0
Chemical Descriptors
11
C101H120N30O12
1946.26
12.88
+4
-9.71
-2.209
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
1.82 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 1.82 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Improving the antibacterial activity and selectivity of an ultra short peptide by hydrophobic and hydrophilic amino acid stretches. | Bioorg Med Chem Lett | 2013