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Peptide record

TPDB06245

Antibacterial Antifungal Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB06245
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RLWRRWRRWLR
Physicochemical Analysis
C81H126N32O12
ANDCEQGHIKMFPSTYV
R
1740.10
13.10
6
0
5
+6
-1.81
-2.009
70.91
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
16500
948.22
0
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
0
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
11
C81H126N32O12
1740.10
13.10
+6
-1.81
-2.009
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
400 µM
Hemolytic Cytotoxic
5% Hemolysis | 400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cell specificity, anti-inflammatory activity, and plausible bactericidal mechanism of designed Trp-rich model antimicrobial peptides | Biochim Biophys Acta | 2009