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Peptide record

TPDB06240

Antibacterial Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB06240
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 11-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KKPKLPWLPKK
Physicochemical Analysis
C68H115N17O12
ARNDCEQGHIMFSTYV
K
1362.77
11.12
5
0
3
+5
3.33
-1.600
70.91
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
403.59
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
5
K
0
M
0
F
3
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 5 M: 0 F: 0 P: 3 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
11
C68H115N17O12
1362.77
11.12
+5
3.33
-1.600
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>400 µM
Hemolytic Cytotoxic
10% Hemolysis | >400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Bacterial selectivity and plausible mode of antibacterial action of designed Pro-rich short model antimicrobial peptides. | J Pept Sci | 2008