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Peptide record

TPDB06230

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB06230
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0 Antifungipept CAFPdb pep-lab dbAMP dbAMP 3.0 i2APP HemoPI PD_Hemolysis
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
WKLFKKILKVL
Physicochemical Analysis
C73H122N16O12
ARNDCEQGHMPSTY
K
1415.87
11.00
4
0
7
+4
-0.94
0.582
168.18
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
388.45
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
3
L
4
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
11
C73H122N16O12
1415.87
11.00
+4
-0.94
0.582
Evidence Records 15 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
0% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Sporicidal activity of synthetic antifungal undecapeptides and control of Penicillium rot of apples. | Appl Environ Microbiol | 2009
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
104 µM
Hemolytic Cytotoxic
50% Hemolysis | 104 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Inhibition of plant-pathogenic bacteria by short synthetic cecropin A-melittin hybrid peptides. | Appl Environ Microbiol | 2006
Evidence 3 Activity

Activity

56% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
56% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Sporicidal activity of synthetic antifungal undecapeptides and control of Penicillium rot of apples. | Appl Environ Microbiol | 2009
Evidence 4 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Mouse fibroblasts L929

Target

Mouse fibroblasts L929

Source & Reference

NA
DBAASP
Comparison of the antibacterial effects of a short cationic peptide and 1% silver bioactive glass against extensively drug-resistant bacteria, Pseudomonas aeruginosa and Acinetobacter baumannii, isolated from burn patients. | Amino Acids | 2018
Evidence 5 Activity

Activity

50% Cell death
Toxicity
13 µg/mL
Cytotoxic
50% Cell death | 13 | µg/mL | target cell: Chinese hamster ovary cells CHO

Target

Chinese hamster ovary cells CHO

Source & Reference

NA
DBAASP
Investigation of the antibacterial activity of a short cationic peptide against multidrug-resistant Klebsiella pneumoniae and Salmonella typhimurium strains and its cytotoxicity on eukaryotic cells. | World J Microbiol Biotechnol | 2014
Evidence 6 Activity

Activity

50% Hemolysis
Toxicity
17 µM
Hemolytic Cytotoxic
50% Hemolysis | 17 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Inhibition of plant-pathogenic bacteria by short synthetic cecropin A-melittin hybrid peptides. | Appl Environ Microbiol | 2006
Evidence 7 Activity

Activity

96% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
96% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Sporicidal activity of synthetic antifungal undecapeptides and control of Penicillium rot of apples. | Appl Environ Microbiol | 2009
Evidence 8 Activity

Activity

50% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
50% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Inhibition of plant-pathogenic bacteria by short synthetic cecropin A-melittin hybrid peptides. | Appl Environ Microbiol | 2006
Evidence 9 Activity

Activity

76% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
76% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Sporicidal activity of synthetic antifungal undecapeptides and control of Penicillium rot of apples. | Appl Environ Microbiol | 2009
Evidence 10 Activity

Activity

50% Hemolysis
Toxicity
11 µM
Hemolytic Cytotoxic
50% Hemolysis | 11 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Inhibition of plant-pathogenic bacteria by short synthetic cecropin A-melittin hybrid peptides. | Appl Environ Microbiol | 2006
Evidence 11 Activity

Activity

73% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
73% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Sporicidal activity of synthetic antifungal undecapeptides and control of Penicillium rot of apples. | Appl Environ Microbiol | 2009
Evidence 12 Activity

Activity

50% Hemolysis
Toxicity
30 µM
Hemolytic Cytotoxic
50% Hemolysis | 30 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Inhibition of plant-pathogenic bacteria by short synthetic cecropin A-melittin hybrid peptides. | Appl Environ Microbiol | 2006
Evidence 13 Activity

Activity

90% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
90% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Sporicidal activity of synthetic antifungal undecapeptides and control of Penicillium rot of apples. | Appl Environ Microbiol | 2009
Evidence 14 Activity

Activity

50% Hemolysis
Toxicity
6 µM
Hemolytic Cytotoxic
50% Hemolysis | 6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Inhibition of plant-pathogenic bacteria by short synthetic cecropin A-melittin hybrid peptides. | Appl Environ Microbiol | 2006
Evidence 15 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis