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Peptide record

TPDB06226

Antibacterial Antifungal Hemolysis Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB06226
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
LLKWLLKWLKK
Physicochemical Analysis
C76H125N17O12
ARNDCEQGHIMFPSTYV
L
1468.94
11.00
4
0
7
+4
-2.54
0.145
177.27
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
11000
748.84
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
5
L
4
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 5 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
11
C76H125N17O12
1468.94
11.00
+4
-2.54
0.145
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
5 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
De novo generation of short antimicrobial peptides with simple amino acid composition | Regul Pept | 2011
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis