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Peptide record

TPDB06219

Antibacterial Antifungal Antiparasitic Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB06219
Antibacterial Antifungal Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb dbAMP 3.0
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KLKLLLLLKLK
Physicochemical Analysis
C66H127N15O12
ARNDCEQGHIMFPSTWYV
L
1322.83
11.00
4
0
7
+4
0.04
1.000
248.18
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
7
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 7 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C66H127N15O12
1322.83
11.00
+4
0.04
1.000
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>300 µM
Hemolytic Cytotoxic
50% Hemolysis | >300 | µM | target cell: Bovine erythrocytes

Target

Bovine erythrocytes

Source & Reference

NA
DBAASP
Self-assembling organo-peptide bolaphiles with KLK tripeptide head groups display selective antibacterial activity. | J Pept Sci | 2013
Evidence 2 Activity

Activity

0% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 50 | µg/mL | target cell: Bovine erythrocytes

Target

Bovine erythrocytes

Source & Reference

NA
DBAASP
Novel synthetic antimicrobial peptides effective against methicillin-resistant Staphylococcus aureus. | Biochem J | 1994