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Peptide record

TPDB06213

Antibacterial Anticancer Antifungal Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB06213
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
SLLSLIRKLLT
Physicochemical Analysis
C58H109N15O15
ANDCEQGHMFPWYV
L
1256.59
11.49
2
0
6
+2
-0.91
1.164
212.73
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
5
L
1
K
0
M
0
F
0
P
2
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 5 K: 1 M: 0 F: 0 P: 0 S: 2 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C58H109N15O15
1256.59
11.49
+2
-0.91
1.164
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
25.0 µM
Hemolytic Cytotoxic
0% Hemolysis | 25.0 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activity of leucine-substituted decoralin analogs with lower hemolytic activity. | J Pept Sci | 2017
Evidence 2 Activity

Activity

50% Cell death
Toxicity
100 µM
Cytotoxic
50% Cell death | 100 | µM | target cell: Normal breast cells MCF-10a

Target

Normal breast cells MCF-10a

Source & Reference

NA
DBAASP
Natural and redesigned wasp venom peptides with selective antitumoral activity. | Beilstein J Org Chem | 2018