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Peptide record

TPDB06187

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB06187
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RGRRSSRRKK
Physicochemical Analysis
C50H99N27O13
ANDCEQHILMFPTWYV
R
1286.51
13.01
7
0
0
+7
6.30
-3.230
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C50H99N27O13
1286.51
13.01
+7
6.30
-3.230
Evidence Records 1 records
Evidence 1 Activity

Activity

<2% Hemolysis
Toxicity
1000 µg/mL
Hemolytic Cytotoxic
<2% Hemolysis | 1000 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Role of acetylation and charge in antimicrobial peptides based on human beta-defensin-3. | APMIS | 2009