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Peptide record

TPDB06178

Antibacterial Anticancer Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB06178
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KKWRKWLAKK
Physicochemical Analysis
C67H110N20O11
NDCEQGHIMFPSTYV
K
1371.74
11.85
6
0
4
+6
1.33
-2.020
49.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11000
801.90
0
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
5
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
10
C67H110N20O11
1371.74
11.85
+6
1.33
-2.020
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
>100 µM
Cytotoxic
50% Cell death | >100 | µM | target cell: Human diploid fibroblasts HFW

Target

Human diploid fibroblasts HFW

Source & Reference

NA
DBAASP
Novel antimicrobial peptides with high anticancer activity and selectivity. | PLoS One | 2015
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel antimicrobial peptides with high anticancer activity and selectivity. | PLoS One | 2015