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Peptide record

TPDB06170

Antibacterial Hemolysis Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB06170
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
KLKLKLKLKL
Physicochemical Analysis
C60H117N15O11
ARNDCEQGHIMFPSTWYV
LK
1224.68
11.12
5
0
5
+5
2.15
-0.050
195.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
5
L
5
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 5 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C60H117N15O11
1224.68
11.12
+5
2.15
-0.050
Evidence Records 6 records
Evidence 1 Activity

Activity

12% Hemolysis
Toxicity
2 µg/mL
Hemolytic Cytotoxic
12% Hemolysis | 2 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Phosphate-dependent aggregation of [KL]n peptides affects their membranolytic activity. | Sci Rep | 2020
Evidence 2 Activity

Activity

20% Hemolysis
Toxicity
8 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | 8 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Phosphate-dependent aggregation of [KL]n peptides affects their membranolytic activity. | Sci Rep | 2020
Evidence 3 Activity

Activity

40% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
40% Hemolysis | 32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Phosphate-dependent aggregation of [KL]n peptides affects their membranolytic activity. | Sci Rep | 2020
Evidence 4 Activity

Activity

81% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
81% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Phosphate-dependent aggregation of [KL]n peptides affects their membranolytic activity. | Sci Rep | 2020
Evidence 5 Activity

Activity

94% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
94% Hemolysis | 256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Phosphate-dependent aggregation of [KL]n peptides affects their membranolytic activity. | Sci Rep | 2020
Evidence 6 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis