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Peptide record

TPDB06162

Antibacterial Antifungal Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB06162
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb DRAMP dbAMP ToxinPred 3.0
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
SRSELIVHQR
Physicochemical Analysis
C51H89N19O16
ANDCGKMFPTWY
RS
1224.39
10.89
3
1
3
+1
4.64
-0.830
107.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
1
E
1
Q
0
G
1
H
1
I
1
L
0
K
0
M
0
F
0
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 1 I: 1 L: 1 K: 0 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
10
C51H89N19O16
1224.39
10.89
+1
4.64
-0.830
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
20 µM

Target

B. cinerea

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
DRAMP antibacterial activity supported by MIC records against bacterial target organisms. dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against B. cinerea (MIC 20 uM), F. oxysporum (MIC 20 uM), A. niger (MIC 41 uM), C. albicans 01U or 38U (MIC 7-13 uM), C.
Evidence 2 Activity

Activity

MIC
Antibacterial
20 µM

Target

F. oxysporum

Source & Reference

dbAMP DRAMP

Other

Active against B. cinerea (MIC 20 uM), F. oxysporum (MIC 20 uM), A. niger (MIC 41 uM), C. albicans 01U or 38U (MIC 7-13 uM), C.parapsilosis (MIC 105 uM),
Evidence 3 Activity

Activity

MIC
Antibacterial
41 µM

Target

A. niger

Source & Reference

dbAMP DRAMP

Other

Active against B. cinerea (MIC 20 uM), F. oxysporum (MIC 20 uM), A. niger (MIC 41 uM), C. albicans 01U or 38U (MIC 7-13 uM), C.parapsilosis (MIC 105 uM), C.neoformans (MIC 209
Evidence 4 Activity

Activity

MIC
Antibacterial
7-13 µM

Target

Candida albicans 01U or 38U

Source & Reference

dbAMP DRAMP

Other

Active against B. cinerea (MIC 20 uM), F. oxysporum (MIC 20 uM), A. niger (MIC 41 uM), C. albicans 01U or 38U (MIC 7-13 uM), C.parapsilosis (MIC 105 uM), C.neoformans (MIC 209 uM), and T. rubrum (MIC 3 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
105 µM

Target

C.parapsilosis

Source & Reference

dbAMP DRAMP

Other

M), F. oxysporum (MIC 20 uM), A. niger (MIC 41 uM), C. albicans 01U or 38U (MIC 7-13 uM), C.parapsilosis (MIC 105 uM), C.neoformans (MIC 209 uM), and T. rubrum (MIC 3 uM).
Evidence 6 Activity

Activity

MIC
Antibacterial
209 µM

Target

C.neoformans

Source & Reference

dbAMP DRAMP

Other

A. niger (MIC 41 uM), C. albicans 01U or 38U (MIC 7-13 uM), C.parapsilosis (MIC 105 uM), C.neoformans (MIC 209 uM), and T. rubrum (MIC 3 uM).
Evidence 7 Activity

Activity

MIC
Antibacterial
3 µM

Target

T. rubrum

Source & Reference

dbAMP DRAMP

Other

ans 01U or 38U (MIC 7-13 uM), C.parapsilosis (MIC 105 uM), C.neoformans (MIC 209 uM), and T. rubrum (MIC 3 uM).
Evidence 8 Activity

Activity

MIC
Antifungal
20 µM

Target

B. cinerea

Source & Reference

dbAMP DRAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
DRAMP antifungal activity supported by activity records against fungal target organisms. dbAMP classified under the Anti-fungal function class.
Active against B. cinerea (MIC 20 uM), F. oxysporum (MIC 20 uM), A. niger (MIC 41 uM), C. albicans 01U or 38U (MIC 7-13 uM), C.
Evidence 9 Activity

Activity

MIC
Antifungal
20 µM

Target

F. oxysporum

Source & Reference

dbAMP DRAMP CAFPdb

Other

Active against B. cinerea (MIC 20 uM), F. oxysporum (MIC 20 uM), A. niger (MIC 41 uM), C. albicans 01U or 38U (MIC 7-13 uM), C.parapsilosis (MIC 105 uM),
Evidence 10 Activity

Activity

MIC
Antifungal
41 µM

Target

A. niger

Source & Reference

dbAMP DRAMP CAFPdb

Other

Active against B. cinerea (MIC 20 uM), F. oxysporum (MIC 20 uM), A. niger (MIC 41 uM), C. albicans 01U or 38U (MIC 7-13 uM), C.parapsilosis (MIC 105 uM), C.neoformans (MIC 209
Evidence 11 Activity

Activity

MIC
Antifungal
7-13 µM

Target

Candida albicans 01U or 38U

Source & Reference

dbAMP DRAMP CAFPdb

Other

Active against B. cinerea (MIC 20 uM), F. oxysporum (MIC 20 uM), A. niger (MIC 41 uM), C. albicans 01U or 38U (MIC 7-13 uM), C.parapsilosis (MIC 105 uM), C.neoformans (MIC 209 uM), and T. rubrum (MIC 3 uM).
Evidence 12 Activity

Activity

MIC
Antifungal
105 µM

Target

C.parapsilosis

Source & Reference

dbAMP DRAMP CAFPdb

Other

M), F. oxysporum (MIC 20 uM), A. niger (MIC 41 uM), C. albicans 01U or 38U (MIC 7-13 uM), C.parapsilosis (MIC 105 uM), C.neoformans (MIC 209 uM), and T. rubrum (MIC 3 uM).
Evidence 13 Activity

Activity

MIC
Antifungal
209 µM

Target

C.neoformans

Source & Reference

dbAMP DRAMP CAFPdb

Other

A. niger (MIC 41 uM), C. albicans 01U or 38U (MIC 7-13 uM), C.parapsilosis (MIC 105 uM), C.neoformans (MIC 209 uM), and T. rubrum (MIC 3 uM).
Evidence 14 Activity

Activity

MIC
Antifungal
3 µM

Target

T. rubrum

Source & Reference

dbAMP DRAMP CAFPdb

Other

ans 01U or 38U (MIC 7-13 uM), C.parapsilosis (MIC 105 uM), C.neoformans (MIC 209 uM), and T. rubrum (MIC 3 uM).
Evidence 15 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Functional characterization of a synthetic hydrophilic antifungal peptide derived from the marine snail Cenchritis muricatus. | Biochimie | 2012
Evidence 16 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: [Ref.22210491] At the highest evaluated dose (256 µg/mL), Cm-p1 showed no signs of toxicity against human red blood cells. | Cytotoxicity: [Ref.22210491] At the highest evaluated dose (256 µg/mL), Cm-p1 showed no signs of toxicity against RAW 264.7 cells.

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochimie. 2012 Apr 94(4):968-974.