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Peptide record

TPDB06157

Neurokinin A Neurokinin-A Antibacterial Anticancer Antifungal Antiparasitic Antiviral Neuropeptide Toxicity standard

10 amino acids

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB06157

Peptide_Name

Neurokinin A Neurokinin-A

Activity

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Neuropeptide Toxicity

Activity_category_statistics

Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Neuroactive peptides

Database_Source

AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF CAFPdb AI4AVP pep-lab

Sequence_Type

standard

Has_Modification No

Description A 10-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.

Sequence

HKTDSFVGLM

FASTA

>TPDB06157|Antibacterial;Anticancer;Antifungal;Antiparasitic;Antiviral;Neuropeptide;Toxicity|length=10
HKTDSFVGLM

Formula C50H79N13O15S1

Absent Amino Acids ARNCEQIPWY

Common Amino Acids DGHLKMFSTV

Mass 1134.32

PI 7.81

Basic Residues 2

Acidic Residues 1

Hydrophobic Residues 4

Net Charge +0

Boman Index 1.61

Hydrophobicity 0.020

Aliphatic Index 68.00

Half Life

Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 0

Absorbance 280nm 0.00

Polar Residues 2

number

Amino Acid Distribution

A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 1 K: 1 M: 1 F: 1 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 1

Length

Formula

C50H79N13O15S1

Mass

1134.32

7.81

Net Charge

Boman Index

1.61

Hydrophobicity

0.020

Evidence 1 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Coturnix japonica

Family Tachykinin

Evidence 2 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Substance-K receptor

Receptor Organisms Bos taurus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Bos taurus

Family Tachykinin

Receptor Lengths 384

Receptor Ligands NP10670

Evidence 3 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Substance-P receptor Substance-K receptor Neuromedin-K receptor

Receptor Organisms Homo sapiens Homo sapiens Homo sapiens

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Homo sapiens

Family Tachykinin

Receptor Lengths 407 398 465

Receptor Ligands NP10738 NP10746 NP10672 NP10682 NP10738 NP10746 NP10672 NP10682 NP10738 NP10746 NP10672 NP10682

Evidence 4 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Substance-K receptor

Receptor Organisms Mesocricetus auratus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Mesocricetus auratus

Family Tachykinin

Receptor Lengths 384

Receptor Ligands NP10673

Evidence 5 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Substance-K receptor

Receptor Organisms Mus musculus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Mus musculus

Family Tachykinin

Receptor Lengths 384

Receptor Ligands NP10674

Evidence 6 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Substance-K receptor

Receptor Organisms Oryctolagus cuniculus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Oryctolagus cuniculus

Family Tachykinin

Receptor Lengths 384

Receptor Ligands NP10675

Evidence 7 Activity

Activity

Detail Source Activity Neuropeptide

Target

Receptor Names Substance-K receptor

Receptor Organisms Rattus norvegicus

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Rattus norvegicus

Family Tachykinin

Receptor Lengths 390

Receptor Ligands NP10676

Evidence 8 Activity

Activity

Detail Source Activity Neuropeptide

Source & Reference

Database Source NA

Source NeuroPepV2

Other

Organism Source Gallus gallus

Family Tachykinin

Family

Tachykinin

Receptor_Lengths

384 407 398 465 390

Receptor_Ligands

NP10670 NP10738 NP10746 NP10672 NP10682 NP10673 NP10674 NP10675 NP10676