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Peptide record

TPDB06145

Antibacterial Antifungal Antiviral Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB06145
Antibacterial Antifungal Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb DRAMP dbAMP DRAVP 2.0 ToxinPred 3.0
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Antifungal, Antiviral, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
IIIQYEGHKH
Physicochemical Analysis
C57H88N16O15
ARNDCLMFPSTWV
I
1237.42
7.90
3
1
4
+0
3.65
-0.550
117.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
1490
120.41
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
1
Q
1
G
2
H
3
I
0
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 1 H: 2 I: 3 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
10
C57H88N16O15
1237.42
7.90
+0
3.65
-0.550
Evidence Records 20 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1.1 µM

Target

B. bassiana Trichosporon sp IOC4569

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
DRAMP antibacterial activity supported by MIC records against bacterial target organisms. dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against fungi B. bassiana Trichosporon sp IOC4569 (MIC 1.1 uM), yeasts C. albicans MDM8 or IOC 4558 (MIC 8.37-16.75 uM), C. krusei IOC 4559 (MIC 16.75 u
Evidence 2 Activity

Activity

MIC
Antibacterial
8.37-16.75 µM

Target

Candida albicans MDM8 or IOC 4558

Source & Reference

dbAMP DRAMP

Other

Active against fungi B. bassiana Trichosporon sp IOC4569 (MIC 1.1 uM), yeasts C. albicans MDM8 or IOC 4558 (MIC 8.37-16.75 uM), C. krusei IOC 4559 (MIC 16.75 uM), C. glabrata IOC 4565 (MIC MIC 8.37 uM), C. parapsilos
Evidence 3 Activity

Activity

MIC
Antibacterial
16.75 µM

Target

C. krusei IOC 4559

Source & Reference

dbAMP DRAMP

Other

osporon sp IOC4569 (MIC 1.1 uM), yeasts C. albicans MDM8 or IOC 4558 (MIC 8.37-16.75 uM), C. krusei IOC 4559 (MIC 16.75 uM), C. glabrata IOC 4565 (MIC MIC 8.37 uM), C. parapsilosis IOC 4564 (MIC 16.75 uM), C. trop
Evidence 4 Activity

Activity

MIC
Antibacterial
16.75 µM

Target

C. parapsilosis IOC 4564

Source & Reference

dbAMP DRAMP

Other

.37-16.75 uM), C. krusei IOC 4559 (MIC 16.75 uM), C. glabrata IOC 4565 (MIC MIC 8.37 uM), C. parapsilosis IOC 4564 (MIC 16.75 uM), C. tropicalis IOC 4560 (MIC 8.75 uM), and C. guilliermondii IOC 4557 (MIC 16.75 uM). It
Evidence 5 Activity

Activity

MIC
Antibacterial
8.75 µM

Target

C. tropicalis IOC 4560

Source & Reference

dbAMP DRAMP

Other

.75 uM), C. glabrata IOC 4565 (MIC MIC 8.37 uM), C. parapsilosis IOC 4564 (MIC 16.75 uM), C. tropicalis IOC 4560 (MIC 8.75 uM), and C. guilliermondii IOC 4557 (MIC 16.75 uM). It binds yeast DNA but bit bacteria. No a
Evidence 6 Activity

Activity

MIC
Antibacterial
16.75 µM

Target

C. guilliermondii IOC 4557

Source & Reference

dbAMP DRAMP

Other

7 uM), C. parapsilosis IOC 4564 (MIC 16.75 uM), C. tropicalis IOC 4560 (MIC 8.75 uM), and C. guilliermondii IOC 4557 (MIC 16.75 uM). It binds yeast DNA but bit bacteria. No antibacterial activity against M-luteus, S-aureu
Evidence 7 Activity

Activity

MIC
Antifungal
1.1 µM

Target

B. bassiana Trichosporon sp IOC4569

Source & Reference

dbAMP DRAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
DRAMP antifungal activity supported by activity records against fungal target organisms. dbAMP classified under the Anti-fungal function class.
Active against fungi B. bassiana Trichosporon sp IOC4569 (MIC 1.1 uM), yeasts C. albicans MDM8 or IOC 4558 (MIC 8.37-16.75 uM), C. krusei IOC 4559 (MIC 16.75 u
Evidence 8 Activity

Activity

MIC
Antifungal
8.37-16.75 µM

Target

Candida albicans MDM8 or IOC 4558

Source & Reference

dbAMP DRAMP CAFPdb

Other

Active against fungi B. bassiana Trichosporon sp IOC4569 (MIC 1.1 uM), yeasts C. albicans MDM8 or IOC 4558 (MIC 8.37-16.75 uM), C. krusei IOC 4559 (MIC 16.75 uM), C. glabrata IOC 4565 (MIC MIC 8.37 uM), C. parapsilos
Evidence 9 Activity

Activity

MIC
Antifungal
16.75 µM

Target

C. krusei IOC 4559

Source & Reference

dbAMP DRAMP CAFPdb

Other

osporon sp IOC4569 (MIC 1.1 uM), yeasts C. albicans MDM8 or IOC 4558 (MIC 8.37-16.75 uM), C. krusei IOC 4559 (MIC 16.75 uM), C. glabrata IOC 4565 (MIC MIC 8.37 uM), C. parapsilosis IOC 4564 (MIC 16.75 uM), C. trop
Evidence 10 Activity

Activity

MIC
Antifungal
16.75 µM

Target

C. parapsilosis IOC 4564

Source & Reference

dbAMP DRAMP CAFPdb

Other

.37-16.75 uM), C. krusei IOC 4559 (MIC 16.75 uM), C. glabrata IOC 4565 (MIC MIC 8.37 uM), C. parapsilosis IOC 4564 (MIC 16.75 uM), C. tropicalis IOC 4560 (MIC 8.75 uM), and C. guilliermondii IOC 4557 (MIC 16.75 uM). It
Evidence 11 Activity

Activity

MIC
Antifungal
8.75 µM

Target

C. tropicalis IOC 4560

Source & Reference

dbAMP DRAMP CAFPdb

Other

.75 uM), C. glabrata IOC 4565 (MIC MIC 8.37 uM), C. parapsilosis IOC 4564 (MIC 16.75 uM), C. tropicalis IOC 4560 (MIC 8.75 uM), and C. guilliermondii IOC 4557 (MIC 16.75 uM). It binds yeast DNA but bit bacteria. No a
Evidence 12 Activity

Activity

MIC
Antifungal
16.75 µM

Target

C. guilliermondii IOC 4557

Source & Reference

dbAMP DRAMP CAFPdb

Other

7 uM), C. parapsilosis IOC 4564 (MIC 16.75 uM), C. tropicalis IOC 4560 (MIC 8.75 uM), and C. guilliermondii IOC 4557 (MIC 16.75 uM). It binds yeast DNA but bit bacteria. No antibacterial activity against M-luteus, S-aureu
Evidence 13 Activity

Activity

MIC
Antiviral
1.1 µM

Target

B. bassiana Trichosporon sp IOC4569

Source & Reference

DRAMP DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against fungi B. bassiana Trichosporon sp IOC4569 (MIC 1.1 uM), yeasts C. albicans MDM8 or IOC 4558 (MIC 8.37-16.75 uM), C. krusei IOC 4559 (MIC 16.75 u
Evidence 14 Activity

Activity

MIC
Antiviral
8.37-16.75 µM

Target

Candida albicans MDM8 or IOC 4558

Source & Reference

DRAMP DRAVP 2.0

Other

Active against fungi B. bassiana Trichosporon sp IOC4569 (MIC 1.1 uM), yeasts C. albicans MDM8 or IOC 4558 (MIC 8.37-16.75 uM), C. krusei IOC 4559 (MIC 16.75 uM), C. glabrata IOC 4565 (MIC MIC 8.37 uM), C. parapsilos
Evidence 15 Activity

Activity

MIC
Antiviral
16.75 µM

Target

C. krusei IOC 4559

Source & Reference

DRAMP DRAVP 2.0

Other

osporon sp IOC4569 (MIC 1.1 uM), yeasts C. albicans MDM8 or IOC 4558 (MIC 8.37-16.75 uM), C. krusei IOC 4559 (MIC 16.75 uM), C. glabrata IOC 4565 (MIC MIC 8.37 uM), C. parapsilosis IOC 4564 (MIC 16.75 uM), C. trop
Evidence 16 Activity

Activity

MIC
Antiviral
16.75 µM

Target

C. parapsilosis IOC 4564

Source & Reference

DRAMP DRAVP 2.0

Other

.37-16.75 uM), C. krusei IOC 4559 (MIC 16.75 uM), C. glabrata IOC 4565 (MIC MIC 8.37 uM), C. parapsilosis IOC 4564 (MIC 16.75 uM), C. tropicalis IOC 4560 (MIC 8.75 uM), and C. guilliermondii IOC 4557 (MIC 16.75 uM). It
Evidence 17 Activity

Activity

MIC
Antiviral
8.75 µM

Target

C. tropicalis IOC 4560

Source & Reference

DRAMP DRAVP 2.0

Other

.75 uM), C. glabrata IOC 4565 (MIC MIC 8.37 uM), C. parapsilosis IOC 4564 (MIC 16.75 uM), C. tropicalis IOC 4560 (MIC 8.75 uM), and C. guilliermondii IOC 4557 (MIC 16.75 uM). It binds yeast DNA but bit bacteria. No a
Evidence 18 Activity

Activity

MIC
Antiviral
16.75 µM

Target

C. guilliermondii IOC 4557

Source & Reference

DRAMP DRAVP 2.0

Other

7 uM), C. parapsilosis IOC 4564 (MIC 16.75 uM), C. tropicalis IOC 4560 (MIC 8.75 uM), and C. guilliermondii IOC 4557 (MIC 16.75 uM). It binds yeast DNA but bit bacteria. No antibacterial activity against M-luteus, S-aureu
Evidence 19 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rondonin an antifungal peptide from spider (Acanthoscurria rondoniae) haemolymph. | Results Immunol | 2012
Evidence 20 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Swiss_Prot Entry B3EWP8]Non-hemolytic activity

Target

erythrocytes

Source & Reference

NA
DRAMP
Results Immunol. 2012 2:66-71.