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Peptide record

TPDB06127

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB06127
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ILGKIIKVVK
Physicochemical Analysis
C54H103N13O11
ARNDCEQHMFPSTWY
IK
1110.49
10.84
3
0
6
+3
1.63
1.360
214.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
1
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 1 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
10
C54H103N13O11
1110.49
10.84
+3
1.63
1.360
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Lasioglossins: three novel antimicrobial peptides from the venom of the eusocial bee Lasioglossum laticeps (Hymenoptera: Halictidae). | Chembiochem | 2009
Evidence 2 Activity

Activity

LC50
Toxicity
200 µM
Hemolytic
Hemolytic_activity: [Ref.19591185]LC50>200 µM against rat red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Chembiochem. 2009 Aug 17 10(12):2089-2117.