Back to search

Peptide record

TPDB06126

Antibacterial Antifungal Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB06126
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia CAFPdb ToxinPred 3.0
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLTRLFSVIK
Physicochemical Analysis
C53H92N14O13
ANDCEQHMPWY
L
1133.40
11.49
2
0
5
+2
-0.41
0.880
146.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
1
K
0
M
1
F
0
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 1 M: 0 F: 1 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
10
C53H92N14O13
1133.40
11.49
+2
-0.41
0.880
Evidence Records 13 records
Evidence 1 Activity

Activity

MIC
Antibacterial
16.7-33.5 µM

Target

L. innocua CICC 10417

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram+ bacteria B. subtilis CICC 10034, S. aureus CICC 10306, L. innocua CICC 10417 (MIC 16.7-33.5 uM) Gram- bacteria E. coli CICC 10293, P:. aeruginosa CICC 21636, S. marcescens ATCC 4112, E
Evidence 2 Activity

Activity

MIC
Antibacterial
8.3-33.3 µM

Target

S. Paratyphi CICC 10437

Source & Reference

dbAMP DRAMP

Other

ICC 10293, P:. aeruginosa CICC 21636, S. marcescens ATCC 4112, E. cloacae CICC 21539, and S. Paratyphi CICC 10437 (MIC 8.3-33.3 uM), fungi A. niger CICC 2124, C. albicans CICC 1965, and S. cerevisiae CICC 1002 (MIC 33.4-6
Evidence 3 Activity

Activity

MIC
Antibacterial
33.4-66.8 µM

Target

S. cerevisiae CICC 1002

Source & Reference

dbAMP DRAMP

Other

atyphi CICC 10437 (MIC 8.3-33.3 uM), fungi A. niger CICC 2124, C. albicans CICC 1965, and S. cerevisiae CICC 1002 (MIC 33.4-66.8 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
16.7-33.5 µM

Target

L. innocua CICC 10417

Source & Reference

dbAMP DRAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram+ bacteria B. subtilis CICC 10034, S. aureus CICC 10306, L. innocua CICC 10417 (MIC 16.7-33.5 uM) Gram- bacteria E. coli CICC 10293, P:. aeruginosa CICC 21636, S. marcescens ATCC 4112, E
Evidence 5 Activity

Activity

MIC
Antifungal
8.3-33.3 µM

Target

S. Paratyphi CICC 10437

Source & Reference

dbAMP DRAMP CAFPdb

Other

ICC 10293, P:. aeruginosa CICC 21636, S. marcescens ATCC 4112, E. cloacae CICC 21539, and S. Paratyphi CICC 10437 (MIC 8.3-33.3 uM), fungi A. niger CICC 2124, C. albicans CICC 1965, and S. cerevisiae CICC 1002 (MIC 33.4-6
Evidence 6 Activity

Activity

MIC
Antifungal
33.4-66.8 µM

Target

S. cerevisiae CICC 1002

Source & Reference

dbAMP DRAMP CAFPdb

Other

atyphi CICC 10437 (MIC 8.3-33.3 uM), fungi A. niger CICC 2124, C. albicans CICC 1965, and S. cerevisiae CICC 1002 (MIC 33.4-66.8 uM).
Evidence 7 Activity

Activity

0% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Purification, characterization and application of a novel antimicrobial peptide from Andrias davidianus blood. | Lett Appl Microbiol | 2017
Evidence 8 Activity

Activity

10% Hemolysis
Toxicity
512 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 512 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Purification, characterization and application of a novel antimicrobial peptide from Andrias davidianus blood. | Lett Appl Microbiol | 2017
Evidence 9 Activity

Activity

0% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 64 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Evaluation of Short-Chain Antimicrobial Peptides With Combined Antimicrobial and Anti inflammatory Bioactivities for the Treatment of Zoonotic Skin Pathogens From Canines. | Front Microbiol | 2021
Evidence 10 Activity

Activity

8% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
8% Hemolysis | 256 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Evaluation of Short-Chain Antimicrobial Peptides With Combined Antimicrobial and Anti inflammatory Bioactivities for the Treatment of Zoonotic Skin Pathogens From Canines. | Front Microbiol | 2021
Evidence 11 Activity

Activity

0% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 64 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Evaluation of Short-Chain Antimicrobial Peptides With Combined Antimicrobial and Anti inflammatory Bioactivities for the Treatment of Zoonotic Skin Pathogens From Canines. | Front Microbiol | 2021
Evidence 12 Activity

Activity

<5% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 256 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Evaluation of Short-Chain Antimicrobial Peptides With Combined Antimicrobial and Anti inflammatory Bioactivities for the Treatment of Zoonotic Skin Pathogens From Canines. | Front Microbiol | 2021
Evidence 13 Activity

Activity

% Hemolysis
Toxicity
0 %
Hemolytic
Hemolytic_activity: [Ref.29130500] 0% hemolysis at 64 µg/ml , 0.5% hemolysis at 128 µg/ml , 2% hemolysis at 256 µg/ml , 13% hemolysis at 512 µg/ml against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Lett Appl Microbiol.?2018 Jan 66(1):38-43. doi: 10.1111/lam.12823.