Peptide record

TPDB06118

Antibacterial Antifungal Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB06118
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
CLLKKLLKKC
Physicochemical Analysis
C54H104N14O11S2
ARNDEQGHIMFPSTWYV
LK
1189.63
10.17
4
0
4
+4
1.24
0.460
156.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
10.51
2
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
0
I
4
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C54H104N14O11S2
1189.63
10.17
+4
1.24
0.460
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>2500 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >2500 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
The effect of thiol functional group incorporation into cationic helical peptides on antimicrobial activities and spectra. | Biomaterials | 2011