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Peptide record

TPDB06115

Antibacterial Antifungal Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB06115
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia CAFPdb
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KLLKFIKKLL
Physicochemical Analysis
C63H114N14O11
ARNDCEQGHMPSTWYV
LK
1243.69
11.00
4
0
6
+4
0.28
0.690
195.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
4
L
4
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 4 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C63H114N14O11
1243.69
11.00
+4
0.28
0.690
Evidence Records 4 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and biological activity of lipophilic analogs of the cationic antimicrobial active peptide anoplin. | J Pept Sci | 2016
Evidence 2 Activity

Activity

5% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and biological activity of lipophilic analogs of the cationic antimicrobial active peptide anoplin. | J Pept Sci | 2016
Evidence 3 Activity

Activity

10% Hemolysis
Toxicity
300 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 300 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and biological activity of lipophilic analogs of the cationic antimicrobial active peptide anoplin. | J Pept Sci | 2016
Evidence 4 Activity

Activity

% Hemolysis
Toxicity
0 %
Hemolytic
Hemolytic_activity: [Ref.27862650]0% hemolysis at 100 µg/ml , 4% hemolysis at 200 µg/ml , 11% hemolysis at 300 µg/ml , 13% hemolysis at 400 µg/ml , 15% hemolysis at 500 µg/ml against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
J Pept Sci. 2016 Nov 22(11-12):731-736. doi: 10.1002/psc.2939.