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Peptide record

TPDB06103

Antibacterial standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB06103
Antibacterial
Anti-infective peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard-residue antibacterial peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
QKKARVRLSA
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C49H93N19O13
NDCEGHIMFPTWY
ARK
1156.40
12.42
4
0
4
+4
3.73
-0.950
88.00
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
2
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
1
L
2
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
10 reviewed residue count
C49H93N19O13 sequence-only estimate (linear, free termini)
1156.40 sequence-only estimate (linear, free termini)
12.42 sequence-only estimate (linear, free termini)
+4 sequence-only estimate (linear, free termini)
3.73 sequence-only estimate (linear, free termini)
-0.950 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

NA

Other

active against E-coli ATCC 25922 (MIC >64 ug/ml), P. aeruginosa ATCC 27853 (MIC 64 ug/ml), and S-aureus ATCC 29213 (MIC >64 ug/ml).