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Peptide record

TPDB06092

Antibacterial Antifungal Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB06092
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
ALWKNMLKGI
Physicochemical Analysis
C55H92N14O12S1
RDCEQHFPSTYV
LK
1173.48
10.60
2
0
6
+2
-1.27
0.320
127.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
468.69
1
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
2
K
1
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 2 M: 1 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
10
C55H92N14O12S1
1173.48
10.60
+2
-1.27
0.320
Evidence Records 1 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
>150 µM
Hemolytic Cytotoxic
100% Hemolysis | >150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The vertebrate peptide antibiotics dermaseptins have overlapping structural features but target specific microorganisms. | J Biol Chem | 1994