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Peptide record

TPDB06065

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB06065
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
IKKIIKKIIK
Physicochemical Analysis
C60H117N15O11
ARNDCEQGHLMFPSTWYV
IK
1224.68
11.12
5
0
5
+5
3.40
0.300
195.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
5
I
0
L
5
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 5 L: 0 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C60H117N15O11
1224.68
11.12
+5
3.40
0.300
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>2000 µM
Hemolytic Cytotoxic
50% Hemolysis | >2000 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Disruption of drug-resistant biofilms using de novo designed short ?-helical antimicrobial peptides with idealized facial amphiphilicity. | Acta Biomater | 2017