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Peptide record

TPDB06053

Antibacterial Hemolysis Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB06053
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
GLLKRIKWLL
Physicochemical Analysis
C61H106N16O11
ANDCEQHMFPSTYV
L
1239.61
11.64
3
0
6
+3
-1.60
0.610
195.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
443.69
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
4
L
2
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 4 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
10
C61H106N16O11
1239.61
11.64
+3
-1.60
0.610
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

Active against S. aureus ATCC 25923 (MIC 4 ug/ml) and E. coli ATCC 25922 (MIC 2 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
2 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

Active against S. aureus ATCC 25923 (MIC 4 ug/ml) and E. coli ATCC 25922 (MIC 2 ug/ml).
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
98 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 98 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship study of anoplin. | J Pept Sci | 2005
Evidence 4 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis