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Peptide record

TPDB06042

Antibacterial Antifungal Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB06042
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
GLLKKIKTLL
Physicochemical Analysis
C54H103N13O12
ARNDCEQHMFPSWYV
L
1126.49
10.84
3
0
5
+3
0.57
0.690
195.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
4
L
3
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 4 K: 3 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C54H103N13O12
1126.49
10.84
+3
0.57
0.690
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
22 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus ATCC 25923 (MIC 22 ug/ml) and E. coli ATCC 25922 (MIC 16 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP

Other

Active against S. aureus ATCC 25923 (MIC 22 ug/ml) and E. coli ATCC 25922 (MIC 16 ug/ml).
Evidence 3 Activity

Activity

MIC
Antifungal
22 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus ATCC 25923 (MIC 22 ug/ml) and E. coli ATCC 25922 (MIC 16 ug/ml).
Evidence 4 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP CAFPdb

Other

Active against S. aureus ATCC 25923 (MIC 22 ug/ml) and E. coli ATCC 25922 (MIC 16 ug/ml).
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
1453.13 µM
Hemolytic Cytotoxic
50% Hemolysis | 1453.13 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthetic analogs of anoplin show improved antimicrobial activities. | J Pept Sci | 2013