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Peptide record

TPDB06014

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB06014
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KLLKVIKKLL
Physicochemical Analysis
C59H114N14O11
ARNDCEQGHMFPSTWY
LK
1195.64
11.00
4
0
6
+4
1.48
0.830
224.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
4
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 4 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
10
C59H114N14O11
1195.64
11.00
+4
1.48
0.830
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
9 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

Active against S. aureus ATCC 25923 (MIC 9 ug/ml) and E. coli ATCC 25922 (MIC 6 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
6 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

Active against S. aureus ATCC 25923 (MIC 9 ug/ml) and E. coli ATCC 25922 (MIC 6 ug/ml).
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
231 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 231 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship study of anoplin. | J Pept Sci | 2005