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Peptide record

TPDB05993

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB05993
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RWWRWWRRWW
Physicochemical Analysis
C90H110N28O11
ANDCEQGHILKMFPSTYV
W
1760.04
12.88
4
0
6
+4
-7.86
-2.340
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
33000
1874.95
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
6
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 6 Y: 0 V: 0
Chemical Descriptors
10
C90H110N28O11
1760.04
12.88
+4
-7.86
-2.340
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
1.84 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 1.84 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Improving the antibacterial activity and selectivity of an ultra short peptide by hydrophobic and hydrophilic amino acid stretches. | Bioorg Med Chem Lett | 2013