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Peptide record

TPDB05960

Antibacterial Anticancer Antiparasitic Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB05960
Antibacterial Anticancer Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF dbAMP 3.0
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Anticancer, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AntiCP 2.0, and other sources, with an available 3D structural model.
Sequence
GIIKKIIKKI
Physicochemical Analysis
C56H108N14O11
ARNDCEQHLMFPSTWYV
I
1153.56
11.00
4
0
5
+4
2.42
0.650
195.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
5
I
0
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 5 L: 0 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C56H108N14O11
1153.56
11.00
+4
2.42
0.650
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
>128 µM

Target

S.aureus ATCC 25923

Source & Reference

NA

Other

active against S.aureus ATCC 25923 (MIC >128 uM), B. subtilis ATCC 23857 (MIC 16-30 uM), K.pneumoniae ATCC 700603 (MIC >128 uM), E. coli A
Evidence 2 Activity

Activity

MIC
Antibacterial
16-30 µM

Target

B. subtilis ATCC 23857

Source & Reference

NA

Other

active against S.aureus ATCC 25923 (MIC >128 uM), B. subtilis ATCC 23857 (MIC 16-30 uM), K.pneumoniae ATCC 700603 (MIC >128 uM), E. coli ATCC 25922 (MIC 32 uM), P. aeruginosa AT
Evidence 3 Activity

Activity

MIC
Antibacterial
>128 µM

Target

K.pneumoniae ATCC 700603

Source & Reference

NA

Other

active against S.aureus ATCC 25923 (MIC >128 uM), B. subtilis ATCC 23857 (MIC 16-30 uM), K.pneumoniae ATCC 700603 (MIC >128 uM), E. coli ATCC 25922 (MIC 32 uM), P. aeruginosa ATCC 27853 (MIC 64 uM), A. baumannii ATCC
Evidence 4 Activity

Activity

MIC
Antibacterial
32 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

>128 uM), B. subtilis ATCC 23857 (MIC 16-30 uM), K.pneumoniae ATCC 700603 (MIC >128 uM), E. coli ATCC 25922 (MIC 32 uM), P. aeruginosa ATCC 27853 (MIC 64 uM), A. baumannii ATCC 19606 (MIC 64 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
64 µM

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

NA

Other

7 (MIC 16-30 uM), K.pneumoniae ATCC 700603 (MIC >128 uM), E. coli ATCC 25922 (MIC 32 uM), P. aeruginosa ATCC 27853 (MIC 64 uM), A. baumannii ATCC 19606 (MIC 64 uM).
Evidence 6 Activity

Activity

MIC
Antibacterial
64 µM

Target

A. baumannii ATCC 19606

Source & Reference

NA

Other

0603 (MIC >128 uM), E. coli ATCC 25922 (MIC 32 uM), P. aeruginosa ATCC 27853 (MIC 64 uM), A. baumannii ATCC 19606 (MIC 64 uM).
Evidence 7 Activity

Activity

MIC
Antiparasitic
>128 µM

Target

S.aureus ATCC 25923

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
active against S.aureus ATCC 25923 (MIC >128 uM), B. subtilis ATCC 23857 (MIC 16-30 uM), K.pneumoniae ATCC 700603 (MIC >128 uM), E. coli A
Evidence 8 Activity

Activity

MIC
Antiparasitic
16-30 µM

Target

B. subtilis ATCC 23857

Source & Reference

dbAMP 3.0

Other

active against S.aureus ATCC 25923 (MIC >128 uM), B. subtilis ATCC 23857 (MIC 16-30 uM), K.pneumoniae ATCC 700603 (MIC >128 uM), E. coli ATCC 25922 (MIC 32 uM), P. aeruginosa AT
Evidence 9 Activity

Activity

MIC
Antiparasitic
>128 µM

Target

K.pneumoniae ATCC 700603

Source & Reference

dbAMP 3.0

Other

active against S.aureus ATCC 25923 (MIC >128 uM), B. subtilis ATCC 23857 (MIC 16-30 uM), K.pneumoniae ATCC 700603 (MIC >128 uM), E. coli ATCC 25922 (MIC 32 uM), P. aeruginosa ATCC 27853 (MIC 64 uM), A. baumannii ATCC
Evidence 10 Activity

Activity

MIC
Antiparasitic
32 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP 3.0

Other

>128 uM), B. subtilis ATCC 23857 (MIC 16-30 uM), K.pneumoniae ATCC 700603 (MIC >128 uM), E. coli ATCC 25922 (MIC 32 uM), P. aeruginosa ATCC 27853 (MIC 64 uM), A. baumannii ATCC 19606 (MIC 64 uM).
Evidence 11 Activity

Activity

MIC
Antiparasitic
64 µM

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

dbAMP 3.0

Other

7 (MIC 16-30 uM), K.pneumoniae ATCC 700603 (MIC >128 uM), E. coli ATCC 25922 (MIC 32 uM), P. aeruginosa ATCC 27853 (MIC 64 uM), A. baumannii ATCC 19606 (MIC 64 uM).
Evidence 12 Activity

Activity

MIC
Antiparasitic
64 µM

Target

A. baumannii ATCC 19606

Source & Reference

dbAMP 3.0

Other

0603 (MIC >128 uM), E. coli ATCC 25922 (MIC 32 uM), P. aeruginosa ATCC 27853 (MIC 64 uM), A. baumannii ATCC 19606 (MIC 64 uM).
Evidence 13 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Designed antimicrobial and antitumor peptides with high selectivity. | Biomacromolecules | 2011
Evidence 14 Activity

Activity

10% Hemolysis
Toxicity
>256 µM
Hemolytic Cytotoxic
10% Hemolysis | >256 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
High Therapeutic Index α-Helical AMPs and Their Therapeutic Potential on Bacterial Lung and Skin Wound Infections. | ACS Infect Dis | 2024
Evidence 15 Activity

Activity

IC50
Toxicity
>128 µM
Cytotoxic
IC50 | >128 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
High Therapeutic Index α-Helical AMPs and Their Therapeutic Potential on Bacterial Lung and Skin Wound Infections. | ACS Infect Dis | 2024
Evidence 16 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Biomaterials. 2014 Feb 35(5):1552-61.