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Peptide record

TPDB05946

Antibacterial Hemolysis Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB05946
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
RRRRRWFWFW
Physicochemical Analysis
C81H110N28O11
ANDCEQGHILKMPSTYV
R
1651.95
13.00
5
0
5
+5
-3.76
-1.960
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
16500
998.82
0
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
2
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 2 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
10
C81H110N28O11
1651.95
13.00
+5
-3.76
-1.960
Evidence Records 2 records
Evidence 1 Activity

Activity

31% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
31% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cyclic antimicrobial R-, W-rich peptides: the role of peptide structure and E. coli outer and inner membranes in activity and the mode of action. | Eur Biophys J | 2011
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis