Back to search

Peptide record

TPDB05900

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB05900
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia AntiCP 2.0 iACP-DRLF CAFPdb DRAMP dbAMP ToxinPred 3.0
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AntiCP 2.0, and other sources, with an available 3D structural model.
Sequence
DEKGPKWKR
Physicochemical Analysis
C51H82N16O14
ANCQHILMFSTYV
K
1143.31
10.31
4
2
1
+2
5.64
-2.900
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
5500
481.06
0
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
1
E
0
Q
1
G
0
H
0
I
0
L
3
K
0
M
0
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
9
C51H82N16O14
1143.31
10.31
+2
5.64
-2.900
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
35.2 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
DRAMP antibacterial activity supported by MIC records against bacterial target organisms. dbAMP classified as Antibacterial under the Anti-bacterial function class.
against E-coli (MIC >50 ug/ml), S-aureus (MIC >50 ug/ml), B-subtilis (MIC >50 ug/ml), and C. albicans (MIC 35.2 ug/ml). Aslo histamine release.
Evidence 2 Activity

Activity

MIC
Antifungal
35.2 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
DRAMP antifungal activity supported by activity records against fungal target organisms. dbAMP classified under the Anti-fungal function class.
against E-coli (MIC >50 ug/ml), S-aureus (MIC >50 ug/ml), B-subtilis (MIC >50 ug/ml), and C. albicans (MIC 35.2 ug/ml). Aslo histamine release.
Evidence 3 Activity

Activity

MIC
Antiparasitic
35.2 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
against E-coli (MIC >50 ug/ml), S-aureus (MIC >50 ug/ml), B-subtilis (MIC >50 ug/ml), and C. albicans (MIC 35.2 ug/ml). Aslo histamine release.
Evidence 4 Activity

Activity

0% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Anti-infection peptidomics of amphibian skin. | Mol Cell Proteomics | 2007
Evidence 5 Activity

Activity

(6.2±2.4)% degranulation
Toxicity
50 µg/mL
Cytotoxic
(6.2±2.4)% degranulation | 50 | µg/mL | target cell: Human mast cells

Target

Human mast cells

Source & Reference

NA
DBAASP
Anti-infection peptidomics of amphibian skin. | Mol Cell Proteomics | 2007