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Peptide record

TPDB05896

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB05896
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia SATPdb dbACP CAFPdb dbAMP 3.0 ToxinPred 3.0
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SVAGRAQGM
Physicochemical Analysis
C34H61N13O12S1
NDCEHILKFPTWY
AG
876.00
11.05
1
0
4
+1
1.04
0.011
54.44
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
1
Q
2
G
0
H
0
I
0
L
0
K
1
M
0
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 0 K: 0 M: 1 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
9
C34H61N13O12S1
876.00
11.05
+1
1.04
0.011
Evidence Records 8 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Weakly active against E. coli, B. subtilis, P. aeruginosa, and S. aureus (MIC ~ 80 ug/ml). The antibacterial activity of this series of peptides is Cn-AMP1 > Cn-AMP2 > Cn-AMP3. Cn-AMP1 also displayed antifungal, anticancer, and immune modulating activity ( Silva et al. 2012 ).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Weakly active against E. coli, B. subtilis, P. aeruginosa, and S. aureus (MIC ~ 80 ug/ml). The antibacterial activity of this series of peptides is Cn-AMP1 > Cn-AMP2 > Cn-AMP3. Cn-AMP1 also displayed antifungal, anticancer, and immune modulating activity ( Silva et al. 2012 ).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
Weakly active against E. coli, B. subtilis, P. aeruginosa, and S. aureus (MIC ~ 80 ug/ml). The antibacterial activity of this series of peptides is Cn-AMP1 > Cn-AMP2 > Cn-AMP3. Cn-AMP1 also displayed antifungal, anticancer, and immune modulating activity ( Silva et al. 2012 ).
Evidence 4 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
Weakly active against E. coli, B. subtilis, P. aeruginosa, and S. aureus (MIC ~ 80 ug/ml). The antibacterial activity of this series of peptides is Cn-AMP1 > Cn-AMP2 > Cn-AMP3. Cn-AMP1 also displayed antifungal, anticancer, and immune modulating activity ( Silva et al. 2012 ).
Evidence 5 Activity

Activity

0±0.4% Hemolysis
Toxicity
375 µM
Hemolytic Cytotoxic
0±0.4% Hemolysis | 375 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptide KSL-W and analogues: Promising agents to control plant diseases. | Peptides | 2018
Evidence 6 Activity

Activity

7.7±3.93% Hemolysis
Toxicity
400 µM
Hemolytic Cytotoxic
7.7±3.93% Hemolysis | 400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cn-AMP1: a new promiscuous peptide with potential for microbial infections treatment. | Biopolymers | 2012
Evidence 7 Activity

Activity

0% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
0% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cn-AMP1: a new promiscuous peptide with potential for microbial infections treatment. | Biopolymers | 2012
Evidence 8 Activity

Activity

50% Cell death
Toxicity
>500 µg/mL
Cytotoxic
50% Cell death | >500 | µg/mL | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Linear Antimicrobial Peptides With Activity Against Herpes Simplex Virus 1 and Aichi Virus | Biopolymers | 2017