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Peptide record

TPDB05880

Antibacterial Antifungal Hemolysis Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB05880
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
WVLVLRLGY
Physicochemical Analysis
C56H87N13O11
ANDCEQHIKMFPST
L
1118.39
9.88
1
0
7
+1
-3.51
1.411
194.44
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
6990
625.01
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
3
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 3 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 1 V: 2
Chemical Descriptors
9
C56H87N13O11
1118.39
9.88
+1
-3.51
1.411
Evidence Records 3 records
Evidence 1 Activity

Activity

21% Hemolysis
Toxicity
15 µM
Hemolytic Cytotoxic
21% Hemolysis | 15 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity | J Am Chem Soc | 2009
Evidence 2 Activity

Activity

16% Hemolysis
Toxicity
15 µM
Hemolytic Cytotoxic
16% Hemolysis | 15 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity | J Am Chem Soc | 2009
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis