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Peptide record

TPDB05864

Antibacterial Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB05864
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ToxinPred 3.0
standard
No
A 9-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
VGVGGGFGR
Physicochemical Analysis
C35H56N12O10
ANDCEQHILKMPSTWY
G
804.90
11.05
1
0
3
+1
-0.13
0.522
64.44
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
5
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
9
C35H56N12O10
804.90
11.05
+1
-0.13
0.522
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
81 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Weakly active against S. aureus (MIC 81 uM), Gram- E.coli MTCC 2692 (MIC 162 uM), P.aeruginosa MTCC 8076 (MIC 162 uM), and V.cholerae
Evidence 2 Activity

Activity

MIC
Antibacterial
162 µM

Target

E.coli MTCC 2692

Source & Reference

dbAMP DRAMP

Other

Weakly active against S. aureus (MIC 81 uM), Gram- E.coli MTCC 2692 (MIC 162 uM), P.aeruginosa MTCC 8076 (MIC 162 uM), and V.cholerae McV 09 (MIC 162 uM). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
162 µM

Target

P.aeruginosa MTCC 8076

Source & Reference

dbAMP DRAMP

Other

Weakly active against S. aureus (MIC 81 uM), Gram- E.coli MTCC 2692 (MIC 162 uM), P.aeruginosa MTCC 8076 (MIC 162 uM), and V.cholerae McV 09 (MIC 162 uM). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antibacterial
162 µM

Target

V.cholerae McV 09

Source & Reference

dbAMP DRAMP

Other

MIC 81 uM), Gram- E.coli MTCC 2692 (MIC 162 uM), P.aeruginosa MTCC 8076 (MIC 162 uM), and V.cholerae McV 09 (MIC 162 uM). Updated 7/2021
Evidence 5 Activity

Activity

7% Hemolysis
Toxicity
300 µg/mL
Hemolytic Cytotoxic
7% Hemolysis | 300 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of two novel antimicrobial peptides from the cuticular extracts of the ant Trichomyrmex criniceps (Mayr), (Hymenoptera: Formicidae). | Arch Insect Biochem Physiol | 2017
Evidence 6 Activity

Activity

18% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
18% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of two novel antimicrobial peptides from the cuticular extracts of the ant Trichomyrmex criniceps (Mayr), (Hymenoptera: Formicidae). | Arch Insect Biochem Physiol | 2017