Back to search

Peptide record

TPDB05846

Antibacterial standard
9 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB05846
Antibacterial
Anti-infective peptides
AntiBP3 Peptipedia
standard
No
A 9-aa standard natural antibacterial peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KWKIFRRWW
Physicochemical Analysis
C72H100N20O10
ANDCEQGHLMPSTYV
W
1405.71
12.42
4
0
5
+4
-3.39
-1.356
43.33
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
16500
1173.78
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
0
L
2
K
0
M
1
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 2 M: 0 F: 1 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
9
C72H100N20O10
1405.71
12.42
+4
-3.39
-1.356
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1.5-24 µM

Target

Pseudomonas aeruginosa PAO1 or WT or resistant strains

Source & Reference

NA

Other

active against 6 P. aeruginosa PAO1 or WT or resistant strains (MIC 1.5-24 uM), E. cloacae Strain C601 (MIC 6 uM), E. coli ESBL (MIC 12 uM), K. pneumoniae (MIC 97 uM),
Evidence 2 Activity

Activity

MIC
Antibacterial
6 µM

Target

Enterobacter cloacae Strain C601

Source & Reference

NA

Other

active against 6 P. aeruginosa PAO1 or WT or resistant strains (MIC 1.5-24 uM), E. cloacae Strain C601 (MIC 6 uM), E. coli ESBL (MIC 12 uM), K. pneumoniae (MIC 97 uM), S. aureus ATCC 25923 or MRSA (MIC 3
Evidence 3 Activity

Activity

MIC
Antibacterial
12 µM

Target

Escherichia coli ESBL

Source & Reference

NA

Other

inosa PAO1 or WT or resistant strains (MIC 1.5-24 uM), E. cloacae Strain C601 (MIC 6 uM), E. coli ESBL (MIC 12 uM), K. pneumoniae (MIC 97 uM), S. aureus ATCC 25923 or MRSA (MIC 3 uM), and 5 E. faecalis AT
Evidence 4 Activity

Activity

MIC
Antibacterial
97 µM

Target

Klebsiella pneumoniae

Source & Reference

NA

Other

ant strains (MIC 1.5-24 uM), E. cloacae Strain C601 (MIC 6 uM), E. coli ESBL (MIC 12 uM), K. pneumoniae (MIC 97 uM), S. aureus ATCC 25923 or MRSA (MIC 3 uM), and 5 E. faecalis ATCC29212 (MIC 6-97 uM) anti-
Evidence 5 Activity

Activity

MIC
Antibacterial
3 µM

Target

Staphylococcus aureus ATCC 25923 or MRSA

Source & Reference

NA

Other

, E. cloacae Strain C601 (MIC 6 uM), E. coli ESBL (MIC 12 uM), K. pneumoniae (MIC 97 uM), S. aureus ATCC 25923 or MRSA (MIC 3 uM), and 5 E. faecalis ATCC29212 (MIC 6-97 uM) anti-VRE.
Evidence 6 Activity

Activity

MIC
Antibacterial
6-97 µM

Target

Enterococcus faecalis ATCC29212

Source & Reference

NA

Other

BL (MIC 12 uM), K. pneumoniae (MIC 97 uM), S. aureus ATCC 25923 or MRSA (MIC 3 uM), and 5 E. faecalis ATCC29212 (MIC 6-97 uM) anti-VRE.