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Peptide record

TPDB05843

Antibacterial Anticancer Antifungal Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB05843
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
KRRWRIWLV
Physicochemical Analysis
C63H101N21O10
ANDCEQGHMFPSTY
R
1312.63
12.71
4
0
5
+4
-1.08
-0.744
118.89
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11000
838.01
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
1
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 1
Chemical Descriptors
9
C63H101N21O10
1312.63
12.71
+4
-1.08
-0.744
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
230 µg/mL
Cytotoxic
50% Cell death | 230 | µg/mL | target cell: Human osteoblast-like cells

Target

Human osteoblast-like cells

Source & Reference

NA
DBAASP
A short artificial antimicrobial peptide shows potential to prevent or treat bone infections. | Sci Rep | 2017
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Antimicrob Agents Chemother. 2013 May 57(5):2295-303