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Peptide record

TPDB05834

Antibacterial Anticancer Antifungal Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB05834
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
RTKKWIVWI
Physicochemical Analysis
C61H96N16O11
ANDCEQGHLMFPSY
IKW
1229.53
11.64
3
0
5
+3
-1.32
-0.178
118.89
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
894.65
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
2
K
0
M
0
F
0
P
0
S
1
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 1 W: 2 Y: 0 V: 1
Chemical Descriptors
9
C61H96N16O11
1229.53
11.64
+3
-1.32
-0.178
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
120 µg/mL
Cytotoxic
50% Cell death | 120 | µg/mL | target cell: Human osteoblast-like cells

Target

Human osteoblast-like cells

Source & Reference

NA
DBAASP
A short artificial antimicrobial peptide shows potential to prevent or treat bone infections. | Sci Rep | 2017
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Antimicrob Agents Chemother. 2013 May 57(5):2295-303