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Peptide record

TPDB05829

Antibacterial standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB05829
Antibacterial
Anti-infective peptides
AntiBP3 Peptipedia
standard
No
A 9-aa standard natural antibacterial peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RRFKFIRWW
Physicochemical Analysis
C70H99N21O10
ANDCEQGHLMPSTYV
R
1394.69
12.71
4
0
5
+4
-2.85
-1.011
43.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
788.71
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
0
L
1
K
0
M
2
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 1 M: 0 F: 2 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
9
C70H99N21O10
1394.69
12.71
+4
-2.85
-1.011
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.8-49 µM

Target

Pseudomonas aeruginosa PAO1 or WT or resistant strains

Source & Reference

NA

Other

active against 6 P. aeruginosa PAO1 or WT or resistant strains (MIC 0.8-49 uM), E. cloacae Strain C601 (MIC 12 uM), E. coli ESBL (MIC 12 uM), K. pneumoniae (MIC 49 uM),
Evidence 2 Activity

Activity

MIC
Antibacterial
12 µM

Target

Enterobacter cloacae Strain C601

Source & Reference

NA

Other

active against 6 P. aeruginosa PAO1 or WT or resistant strains (MIC 0.8-49 uM), E. cloacae Strain C601 (MIC 12 uM), E. coli ESBL (MIC 12 uM), K. pneumoniae (MIC 49 uM), S. aureus ATCC 25923 or MRSA (MIC 6
Evidence 3 Activity

Activity

MIC
Antibacterial
12 µM

Target

Escherichia coli ESBL

Source & Reference

NA

Other

nosa PAO1 or WT or resistant strains (MIC 0.8-49 uM), E. cloacae Strain C601 (MIC 12 uM), E. coli ESBL (MIC 12 uM), K. pneumoniae (MIC 49 uM), S. aureus ATCC 25923 or MRSA (MIC 6 uM), and 5 E. faecalis AT
Evidence 4 Activity

Activity

MIC
Antibacterial
49 µM

Target

Klebsiella pneumoniae

Source & Reference

NA

Other

nt strains (MIC 0.8-49 uM), E. cloacae Strain C601 (MIC 12 uM), E. coli ESBL (MIC 12 uM), K. pneumoniae (MIC 49 uM), S. aureus ATCC 25923 or MRSA (MIC 6 uM), and 5 E. faecalis ATCC29212 (MIC 6-98 uM) anti-
Evidence 5 Activity

Activity

MIC
Antibacterial
6 µM

Target

Staphylococcus aureus ATCC 25923 or MRSA

Source & Reference

NA

Other

E. cloacae Strain C601 (MIC 12 uM), E. coli ESBL (MIC 12 uM), K. pneumoniae (MIC 49 uM), S. aureus ATCC 25923 or MRSA (MIC 6 uM), and 5 E. faecalis ATCC29212 (MIC 6-98 uM) anti-VRE.
Evidence 6 Activity

Activity

MIC
Antibacterial
6-98 µM

Target

Enterococcus faecalis ATCC29212

Source & Reference

NA

Other

BL (MIC 12 uM), K. pneumoniae (MIC 49 uM), S. aureus ATCC 25923 or MRSA (MIC 6 uM), and 5 E. faecalis ATCC29212 (MIC 6-98 uM) anti-VRE.