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Peptide record

TPDB05811

AMP1 Antibacterial Anticancer Antifungal standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB05811
AMP1
Antibacterial Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
AntiBP3 Peptipedia CancerPPD 2.0 CAFPdb dbAMP
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Anticancer, and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
WKWLKKWIK-NH2
Physicochemical Analysis
C69H102N16O10
ARNDCEQGHMFPSTYV
K
1315.67
11.00
4
0
5
+4
-2.46
-1.111
86.67
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
16500
1254.11
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
4
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
9
C69H102N16O10
1315.67
11.00
+4
-2.46
-1.111
Amidation
L
Linear
Free
Antimicrobial
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 51.1 µM
Anticancer
51.1 µM

Target

Ovarian Cancer
OVCAR-3
Ovary

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023
US11571454 B2

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.