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Peptide record

TPDB05809

Antibacterial standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB05809
Antibacterial
Anti-infective peptides
AntiBP3 Peptipedia
standard
No
A 9-aa standard natural antibacterial peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
WKKWWKRRW
Physicochemical Analysis
C74H102N22O10
ANDCEQGHILMFPSTYV
W
1459.77
12.43
5
0
4
+5
-2.81
-2.700
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
22000
1507.09
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
9
C74H102N22O10
1459.77
12.43
+5
-2.81
-2.700
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1.4-46 µM

Target

Pseudomonas aeruginosa PAO1 or WT or resistant strains

Source & Reference

NA

Other

active against 6 P. aeruginosa PAO1 or WT or resistant strains (MIC 1.4-46 uM), E. cloacae Strain C601 (MIC 23 uM), E. coli ESBL (MIC 3 uM), K. pneumoniae (MIC 46 uM),
Evidence 2 Activity

Activity

MIC
Antibacterial
23 µM

Target

Enterobacter cloacae Strain C601

Source & Reference

NA

Other

active against 6 P. aeruginosa PAO1 or WT or resistant strains (MIC 1.4-46 uM), E. cloacae Strain C601 (MIC 23 uM), E. coli ESBL (MIC 3 uM), K. pneumoniae (MIC 46 uM), S. aureus ATCC 25923 or MRSA (MIC 1.
Evidence 3 Activity

Activity

MIC
Antibacterial
3 µM

Target

Escherichia coli ESBL

Source & Reference

NA

Other

nosa PAO1 or WT or resistant strains (MIC 1.4-46 uM), E. cloacae Strain C601 (MIC 23 uM), E. coli ESBL (MIC 3 uM), K. pneumoniae (MIC 46 uM), S. aureus ATCC 25923 or MRSA (MIC 1.4-39 uM), 5 E. faecalis A
Evidence 4 Activity

Activity

MIC
Antibacterial
46 µM

Target

Klebsiella pneumoniae

Source & Reference

NA

Other

ant strains (MIC 1.4-46 uM), E. cloacae Strain C601 (MIC 23 uM), E. coli ESBL (MIC 3 uM), K. pneumoniae (MIC 46 uM), S. aureus ATCC 25923 or MRSA (MIC 1.4-39 uM), 5 E. faecalis ATCC29212 (MIC 6-93 uM) anti
Evidence 5 Activity

Activity

MIC
Antibacterial
1.4-39 µM

Target

Staphylococcus aureus ATCC 25923 or MRSA

Source & Reference

NA

Other

, E. cloacae Strain C601 (MIC 23 uM), E. coli ESBL (MIC 3 uM), K. pneumoniae (MIC 46 uM), S. aureus ATCC 25923 or MRSA (MIC 1.4-39 uM), 5 E. faecalis ATCC29212 (MIC 6-93 uM) anti-VRE 2 strains MIC =>186 uM (AMP-resistant?).
Evidence 6 Activity

Activity

MIC
Antibacterial
6-93 µM

Target

Enterococcus faecalis ATCC29212

Source & Reference

NA

Other

BL (MIC 3 uM), K. pneumoniae (MIC 46 uM), S. aureus ATCC 25923 or MRSA (MIC 1.4-39 uM), 5 E. faecalis ATCC29212 (MIC 6-93 uM) anti-VRE 2 strains MIC =>186 uM (AMP-resistant?).