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Peptide record

TPDB05799

Antibacterial Anticancer Antifungal Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB05799
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
IKWKRWWWR
Physicochemical Analysis
C74H101N21O10
ANDCEQGHLMFPSTYV
W
1444.75
12.42
4
0
5
+4
-4.11
-1.767
43.33
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
22000
1522.75
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
9
C74H101N21O10
1444.75
12.42
+4
-4.11
-1.767
Evidence Records 2 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
>400 µg/mL
Hemolytic Cytotoxic
<10% Hemolysis | >400 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activity of GN peptides and their mode of action | Biopolymers | 2016
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
10 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes:<10% Hemolysis>400µg/ml | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Antimicrob Agents Chemother. 2015 Jul 59(7):4112-20.