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Peptide record

TPDB05779

Antibacterial Antifungal Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB05779
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
LLWIALRKK
Physicochemical Analysis
C56H97N15O10
NDCEQGHMFPSTYV
L
1140.48
11.64
3
0
6
+3
-1.22
0.500
184.44
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
5500
482.25
0
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
3
L
2
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
9
C56H97N15O10
1140.48
11.64
+3
-1.22
0.500
Evidence Records 2 records
Evidence 1 Activity

Activity

1.5% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
1.5% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and antimicrobial activity of cysteine-free coprisin nonapeptides. | Biochem Biophys Res Commun | 2014
Evidence 2 Activity

Activity

0.08±0.04% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0.08±0.04% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A potent antibacterial activity of new short d-enantiomeric lipopeptide against multi drug resistant bacteria. | Biochim Biophys Acta | 2019