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Peptide record

TPDB05741

Antibacterial Anticancer Cell-penetrating Peptides Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB05741
Antibacterial Anticancer Cell-penetrating Peptides Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CellPPD-MOD CPPsite3.0
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Anticancer, Cell-penetrating Peptides, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CellPPD-MOD, and other sources, with an available 3D structural model.
Sequence
WRRRRRRRR
Physicochemical Analysis
C59H108N34O10
ANDCEQGHILKMFPSTYV
R
1453.73
13.25
8
0
1
+8
4.63
-4.100
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
378.34
0
Residue Composition
number
0
A
8
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
9
C59H108N34O10
1453.73
13.25
+8
4.63
-4.100
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>128 µM
Hemolytic Cytotoxic
50% Hemolysis | >128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial and cell-penetrating properties of penetratin analogs: effect of sequence and secondary structure. | Biochim Biophys Acta | 2013
Evidence 2 Activity

Activity

HD50
Toxicity
128 µM
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: HD50>128 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochim Biophys Acta. 2013 Feb 1828(2):223-32.