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Peptide record

TPDB05719

RL-9 RL9 Antibacterial Cell-penetrating Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB05719
RL-9 RL9
Antibacterial Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CellPPD-MOD CPPsite3.0
standard
No
A 9-aa standard natural multi-activity (Antibacterial and Cell-penetrating Peptides) peptide sequence curated from AntiBP3, Peptipedia, CellPPD-MOD, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
RRLLRRLRR-NH2
Physicochemical Analysis
C54H107N27O10
ANDCEQGHIKMFPSTWYV
R
1294.62
13.10
6
0
3
+6
3.18
-1.733
130.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
3
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 3 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C54H107N27O10
1294.62
13.10
+6
3.18
-1.733
Amidation
L
Cationic Amphiphilic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

CHO-K1

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Fluorophore (Alexa 488)
In vitro
CCTHHHHCC
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

Hek-293, A549

Source & Reference

CPPsite3.0
CPPsite3

Other

Non-natural residues Linear L Amphiphilic
Synthetic
pDNA nanoparticles
Low-gene expression even when adding CaCl4
In vitro
Additional Detail Fields 1 fields
CCTHHHHCC