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Peptide record

TPDB05716

Antibacterial Hemolysis Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB05716
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
RLWLAIWRR
Physicochemical Analysis
C61H96N20O10
NDCEQGHKMFPSTYV
R
1269.56
12.70
3
0
6
+3
-2.87
-0.156
141.11
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
866.44
0
Residue Composition
number
1
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
2
L
0
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
9
C61H96N20O10
1269.56
12.70
+3
-2.87
-0.156
Evidence Records 4 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
100% Hemolysis | 25 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Design of potent 9-mer antimicrobial peptide analogs of protaetiamycine and investigation of mechanism of antimicrobial action. | J Pept Sci | 2009
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
10% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Enantiomeric 9-mer Peptide Analogs of Protaetiamycine With Bacterial Cell Selectivities and Anti-Inflammatory Activities | J Pept Sci | 2011
Evidence 3 Activity

Activity

30% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
30% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Enantiomeric 9-mer Peptide Analogs of Protaetiamycine With Bacterial Cell Selectivities and Anti-Inflammatory Activities | J Pept Sci | 2011
Evidence 4 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis