Peptide record

TPDB05708

Antibacterial Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB05708
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 9-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RKWVAWRNR
Physicochemical Analysis
C58H90N22O11
DCEQGHILMFPSTY
R
1271.49
12.71
4
0
4
+4
0.04
-1.856
43.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
865.12
1
Residue Composition
number
1
A
3
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 1
Chemical Descriptors
9
C58H90N22O11
1271.49
12.71
+4
0.04
-1.856
Evidence Records 3 records
Evidence 1 Activity

Activity

2% Hemolysis
Toxicity
15 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 15 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Improved antimicrobial activity of h-lysozyme (107-115) by rational Ala substitution. | J Pept Sci | 2010
Evidence 2 Activity

Activity

3% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
3% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Improved antimicrobial activity of h-lysozyme (107-115) by rational Ala substitution. | J Pept Sci | 2010
Evidence 3 Activity

Activity

3% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
3% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Improved antimicrobial activity of h-lysozyme (107-115) by rational Ala substitution. | J Pept Sci | 2010