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Peptide record

TPDB05701

Antibacterial Antifungal Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB05701
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
NIQPPCRCC
Physicochemical Analysis
C40H68N14O12S3
ADEGHLKMFSTWYV
C
1033.25
8.02
1
0
1
+1
1.68
-0.300
43.33
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
125
12.10
5
Residue Composition
number
0
A
1
R
1
N
0
D
3
C
0
E
1
Q
0
G
0
H
1
I
0
L
0
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 3 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 0 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C40H68N14O12S3
1033.25
8.02
+1
1.68
-0.300
Evidence Records 5 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
280 µM
Hemolytic Cytotoxic
0% Hemolysis | 280 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Mo-CBP3-PepI, Mo-CBP3-PepII, and Mo-CBP3-PepIII are synthetic antimicrobial peptides active against human pathogens by stimulating ROS generation and increasing plasma membrane permeability | Biochimie | 2019
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Neutralizing Effect of Synthetic Peptides toward SARS-CoV-2. | ACS Omega | 2022
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Neutralizing Effect of Synthetic Peptides toward SARS-CoV-2. | ACS Omega | 2022
Evidence 4 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Mouse fibroblasts L929

Target

Mouse fibroblasts L929

Source & Reference

NA
DBAASP
Neutralizing Effect of Synthetic Peptides toward SARS-CoV-2. | ACS Omega | 2022
Evidence 5 Activity

Activity

<10% Killing
Toxicity
1000 µg/mL
Cytotoxic
<10% Killing | 1000 | µg/mL | target cell: Zebrafish embryos

Target

Zebrafish embryos

Source & Reference

NA
DBAASP
Neutralizing Effect of Synthetic Peptides toward SARS-CoV-2. | ACS Omega | 2022