Back to search

Peptide record

TPDB05683

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB05683
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
AHCLAIGRK
Physicochemical Analysis
C41H73N15O10S1
NDEQMFPSTWYV
A
968.19
10.11
3
0
4
+2
1.32
0.267
108.89
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
1
R
0
N
0
D
1
C
0
E
0
Q
1
G
1
H
1
I
1
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C41H73N15O10S1
968.19
10.11
+2
1.32
0.267
Evidence Records 4 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Purification, cDNA cloning and modification of a defensin from the coconut rhinoceros beetle, Oryctes rhinoceros. | Eur J Biochem | 1999
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Murine macrophages

Target

Murine macrophages

Source & Reference

NA
DBAASP
Purification, cDNA cloning and modification of a defensin from the coconut rhinoceros beetle, Oryctes rhinoceros. | Eur J Biochem | 1999
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Mouse fibroblasts

Target

Mouse fibroblasts

Source & Reference

NA
DBAASP
Purification, cDNA cloning and modification of a defensin from the coconut rhinoceros beetle, Oryctes rhinoceros. | Eur J Biochem | 1999
Evidence 4 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.10561605] Had no hemolytic activity against rabbit erythrocytes

Target

erythrocytes

Source & Reference

NA
DRAMP
Eur. J. Biochem. 1999 266:616-623.