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Peptide record

TPDB05680

Antibacterial Anticancer Antifungal Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB05680
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
RLWKRWWIR
Physicochemical Analysis
C69H102N22O10
ANDCEQGHMFPSTYV
RW
1399.71
12.71
4
0
5
+4
-3.00
-1.311
86.67
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
16500
1178.82
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
1
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
9
C69H102N22O10
1399.71
12.71
+4
-3.00
-1.311
Evidence Records 2 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
<10% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activity of GN peptides and their mode of action | Biopolymers | 2016
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
10 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes:<10% Hemolysis>400µg/ml | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Antimicrob Agents Chemother. 2015 Jul 59(7):4112-20.