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Peptide record

TPDB05656

Antibacterial Anticancer Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB05656
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia
standard
No
A 8-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, and Peptipedia, with an available 3D structural model.
Sequence
FIRSLFFF
Physicochemical Analysis
C57H77N11O10
ANDCEQGHKMPTWYV
F
1076.31
11.05
1
0
6
+1
-4.45
1.775
97.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
0
K
0
M
4
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 0 M: 0 F: 4 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C57H77N11O10
1076.31
11.05
+1
-4.45
1.775
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
Toxicity
>200 µM
Cytotoxic
IC50 | >200 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Structure-Activity Relationship-based Optimization of Small Temporin-SHf Analogs with Potent Antibacterial Activity | ACS Chem Biol | 2015
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
ACS Chem Biol. 2015 Oct 16 10(10):2257-66.