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Peptide record

TPDB05646

Antibacterial Antifungal Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB05646
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia CAFPdb ToxinPred 3.0
standard
No
A 8-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RYPAVGYT
Physicochemical Analysis
C43H63N11O12
NDCEQHILKMFSW
Y
926.04
9.63
1
0
4
+1
-0.57
-0.475
48.75
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
2980
321.80
3
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
1
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 1 W: 0 Y: 2 V: 1
Chemical Descriptors
8
C43H63N11O12
926.04
9.63
+1
-0.57
-0.475
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.9-5.8 ug/mL

Target

Escherichia coli D31

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
C 4112, E. cloacae beta-12, S. serovars. S. enterica subsp. arizonae, E. coli SBS363, and E. coli D31 (MIC 2.9-5.8 ug/mL). Updated 12/30/2018.
Evidence 2 Activity

Activity

MIC
Antifungal
2.9-5.8 ug/mL

Target

Escherichia coli D31

Source & Reference

dbAMP DRAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
C 4112, E. cloacae beta-12, S. serovars. S. enterica subsp. arizonae, E. coli SBS363, and E. coli D31 (MIC 2.9-5.8 ug/mL). Updated 12/30/2018.
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Lacrain: the first antimicrobial peptide from the body extract of the Brazilian centipede Scolopendra viridicornis. | Int J Antimicrob Agents | 2016
Evidence 4 Activity

Activity

% Hemolysis
Toxicity
0 %
Hemolytic
Hemolytic_activity: [Ref.27451089] 0% hemolysis at 0.5-500 µM against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Int J Antimicrob Agents. 2016 Sep 48(3):277-85. doi: 10.1016/j.ijantimicag.2016.05.015.