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Peptide record

TPDB05632

Antibacterial Antifungal Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB05632
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia CAFPdb
standard
No
A 8-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
IRIKIRIK
Physicochemical Analysis
C48H94N16O9
ANDCEQGHLMFPSTWYV
I
1039.38
12.42
4
0
4
+4
2.36
0.150
195.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
4
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 4 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C48H94N16O9
1039.38
12.42
+4
2.36
0.150
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
2000 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 2000 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic β-sheet forming peptide amphiphiles | Biomaterials | 2014
Evidence 2 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.24211081] HC10=2000 mg/L against rabbit red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Biomaterials. 2014 Jan 35(4):1315-25. doi: 10.1016/j.biomaterials.2013.10.053.