Back to search

Peptide record

TPDB05621

Antibacterial Anticancer Antifungal Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB05621
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 8-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
FFFLRRIF
Physicochemical Analysis
C60H84N14O9
ANDCEQGHKMPSTWYV
F
1145.42
12.40
2
0
6
+2
-3.77
1.312
97.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
0
K
0
M
4
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 0 M: 0 F: 4 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C60H84N14O9
1145.42
12.40
+2
-3.77
1.312
Evidence Records 4 records
Evidence 1 Activity

Activity

IC50
Toxicity
152 µM
Cytotoxic
IC50 | 152 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Structure-Activity Relationship-based Optimization of Small Temporin-SHf Analogs with Potent Antibacterial Activity | ACS Chem Biol | 2015
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Structure-Activity Relationship-based Optimization of Small Temporin-SHf Analogs with Potent Antibacterial Activity | ACS Chem Biol | 2015
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
50% Hemolysis | 200 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Structure-Activity Relationship-based Optimization of Small Temporin-SHf Analogs with Potent Antibacterial Activity | ACS Chem Biol | 2015
Evidence 4 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
ACS Chem Biol. 2015 Oct 16 10(10):2257-66.